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1 Threshold Values and Associated Toxic Classifications Method of Classification Type Description Applications Calculation Threshold Non-zero Adverse health Systemic organ Safety (uncertainty) Non-threshold threshold Zero threshold effects unlikely below this level Adverse health effects possible at any dosage level toxicity; germ-cell mutations; developmental and reproductive toxicity Mutagenic and carcinogenic effects factor method Risk analysis method Chapter 13: The Rainbow Correction 247 Figure 13-7: The mag- nificent new Histogram palette.
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